Boehringer Ingelheim Vetmedica, Inc.
Cattle Division
3902 Gene Field Road
St. Joseph, Missouri 64506
- Phone 866-638-2226
- Fax 816-326-9167
ToDAY®
cephapirin sodium
Reduce the Use of Antibiotics
Take the pledge and make one small step today that can make a world of difference tomorrow.
Save Time, Milk and Money
See how short-duration therapy compares to extended therapy protocols.
Abnormal Milk? What's It Really Telling You?
Learn the difference between infection and inflammation.
See comparison
Culturing Tips at Your Fingertips
Tools and information for using culture-based mastitis treatment on your farm.
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See How ToDAY® Can Benefit Your Operation
See how Hillcrest Farms Inc. has benefited from using ToDAY®.
Product Description
An antibiotic mastitis treatment providing bactericidal activity against Gram-positive and Gram-negative bacteria in lactating dairy cows.
- Each 10 mL disposable, ready-to-use syringe contains the active ingredient cephapirin sodium
- Provides control against mastitis-causing pathogens – including penicillin-resistant Staph aureus and Strep agalactiae
- Easy two-tube treatment given 12 hours apart
- Opti-Sert® applicator tip aids in full or partial insertion
Presentations
- Pail containing 144 x 10 mL syringes and 144 convenient single-use alcohol pads.
- Cartons containing 12 x 10 mL syringes with 12 convenient single-use alcohol pads.
Features & Benefits
Intramammary mastitis treatment of Gram-positive infections is widely reported as beneficial,4 so those infections should be the focus of treatment.1
Stop wasting time, milk and money treating Gram-negative and no-growth cases of mastitis. Culture your milk to determine which of those cases will self-treat and which are Gram-positive.
Choosing a short-duration treatment protocol allows you to treat mastitis with less antibiotics than a five- or eight-day protocol without sacrificing efficacy.
Using two tubes instead of five is better for you, better for the cow, and better for consumers.
FOR YOU
Requires less labor, costs your business less money.
FOR THE COW
Fewer days of antibiotic treatment, less time spent in the hospital pen.
FOR THE CONSUMER
Antibiotics used judiciously increases consumer confidence.
Two tubes of ToDAY® given according to the label will result in 60 fewer hours of milk withhold time as compared to using five tubes of SPECTRAMAST LC, therefore reducing time cows spend in the hospital pen by more than 35 percent. Using ToDAY in combination with a culture-based protocol can save a 1,000-cow dairy over $30,000 annually.3
Dosage
Infuse a 10 mL syringe (200 mg of cephapirin activity per syringe) once the quarter has been completely milked out. Repeat once only in 12 hours. For lactating cows only. Read and follow label directions.
Safety Information:
Milk that has been taken from animals during treatment and for 96 hours after the last treatment must not be used for food. Treated animals must not be slaughtered for food until 4 days after the last treatment. Administration of more than the prescribed dose may lead to residue of antibiotic in milk longer than 96 hours.
ToDAY should be administered with caution to subjects that have demonstrated some form of allergy, particularly to penicillin. Such reactions are rare; however, should they occur, consult your veterinarian.
1 Keefe G, MacDonald K, Cameron M. On-farm culture use experience and impact on antimicrobial use. University of Prince Edward Island, Charlottetown, PE, Canada.
2 Schukken YH, Zurakowski MJ, Rauch BJ, et al. Non-inferiority trial comparing a first-generation cephalosporin with a third-generation cephalosporin in the treatment of non-severe clinical mastitis in dairy cows. J Dairy Sci 2013;96(10):6763-6774.
3 Nydam D, Virkler P, Capel M, et al. Pathogen-based treatment decisions for clinical mastitis, in Proceedings. NMC Regional Meeting 2015;1–4.
4 Hess JL, Neuder LM, Sears PM. Rethinking clinical mastitis therapy, in Proceedings. 42nd Annual Meeting of the National Mastitis Council 2003:372-373.
Technical Bulletins
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A Non-Inferiority Trial Comparing a First Generation Cephalosporin with a Third-Generation Cephalosporin in the Treatment of Non-Severe Clinical Mastitis in Dairy Cows.
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Minimum Inhibitory Concentrations (MIC) for Cephalosporin Compounds on Their Active Metabolites for Selected Mastitis Pathogens.
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Randomized Non-Inferiority Clinical Trial Evaluating Three Commercial Dry Cow Mastitis Preparations.