Boehringer Ingelheim Vetmedica, Inc.
3902 Gene Field Road
St. Joseph, Missouri 64506
- Phone 866-638-2226
- Fax 816-326-9167
View the video tutorial to learn how to properly administer TODAY in your dairy.
Dairy producers share how using TODAY helps their herd.
Tools and information you need to start using culture-based mastitis treatment on your farm.
Check out this video that explains how a one-day treatment compares to extended therapy.
From efficacy to the economic benefits and value of using fewer antibiotics, these pages will show you how and why TODAY tubes are what you need to manage mastitis on your dairy.
TODAY (cephapirin sodium) is a cephalosporin which possesses a wide range of antimicrobial activity against gram-positive and gram-negative organisms. Using a convenient, single-day treatment, TODAY saves producers time and money when solving problems related to mastitis.
ToDAY should be administered with caution to subjects which have demonstrated some form of allergy, particularly to penicillin. Such reactions are rare; however, should they occur, consult your veterinarian.
Intramammary mastitis treatments of Gram-positive infections is widely reported as beneficial5, so those infections should be the focus of treatment.2
A recent study showed similar efficacy between TODAY and Spectramast LC.TODAY was not inferior to Spectramast LC for clinical or bacteriological cures.3
Two tubes of TODAY given according to the label will result in 60 fewer hours of milk withhold time as compared to using five tubes of Spectramast LC, and reduce time cows spend in the hospital pen by 35 percent. UsingTODAY can also save a 1,000 cow dairy over $13,000 annually.4
In a recent head-to-head study comparing cephapirin and ceftiofur (the active ingredient in Spectramast LC), the authors concluded, “Herds that do not utilize a culture-based approach for the treatment of clinical mastitis may have an economic benefit from selecting cephapirin with the shorter non-saleable milk duration as the first treatment of choice. This would be particularly true in herds that have an average or below-average incidence of Gram-negative organisms causing clinical mastitis.”3
1 Boddie RL, Nickerson SC and Sutherland SF. New design of mastitis tubes reduces infection. Hoard’s Dairyman 1989;134(13):579.
2 Keefe G, ManDonald K, Cameron M. On-Farm culture use experience and impact on antimicrobial use. University of Prince Edward Island, Charolottetown, PE, Canada.
3 Schukken YH, Zurakowski MJ, Rauch BJ, et al. Non-inferiority trial comparing a first-generation cephalosporin with athird-generation cephalosporin in the treatment of non-severe clinical mastitis in dairy cows.
4 Miltenburg JD, de Lange D, Crauwels AP, et al. Incidence of clinical mastitis in a random sample of dairy herds in the southernNetherlands. Vet Rec 1996;139(9):204–207.
5 Hess JL, Neuder LM, Sears PM. Rethinking clinical mastitis therapy. Presented at the 42nd Annual Meeting of the National Mastitis Council; Jan. 27, 2003; Fort Worth, TX.
The University of Minnesota developed a guide outlining how to conduct cultures on the farm, which eliminates the need to transport milk to a lab, and can be done is as little as 18 hours. From lab setup and collection and sampling methods, to culturing procedures and interpreting the results, this guide is a must-read for anyone interested in culturing on the farm.
When identifying signs of mastitis, it’s important to know how severe a case may be. This grade chart is a quick, at-a-glance tool to help determine the level, or grade, of mastitis infection.
Not all mastitis infections require antibiotic treatment, Knowing which mastitis cases to treat is as easy as following the Culture Guide Protocol. Use this easy-to-read tool every time you culture to make sure treatments are focused on bacteria that are known to respond to antibiotics.
On-farm culturing is growing in popularity due to its efficiencies and economic benefits. To conduct culturing effectively, you need to have the right equipment to set up a lab. Click here for supply list.
Keeping close records of the cultures done on your farm and the resulting treatment protocol you followed is necessary to track treatment success and avoid milk residue violations. Click here for treatment record PDF.
Using all of these tools, and committing to culturing mastitis infections before beginning treatment, help save you time, milk and money.
Mastitis protocols should always be set up under the direction of the herd veterinarian. Please talk with your veterinarian about making milk culturing part of your mastitis treatment protocol.
A Non-Inferiority Trial Comparing a First Generation Cephalosporin with a Third-Generation Cephalosporin in the Treatment of Non-Severe Clinical Mastitis in Dairy Cows.
Minimum Inhibitory Concentrations (MIC) for cephalosporin compounds on their active metabolites for selected mastitis pathogens.
Randomized Non-Inferiority Clinical Trial Evaluating Three Commercial Dry Cow Mastitis Preparations.