Modified Live Vaccine Tutorial

Learn how to properly mix, store, handle and administer Modified Live Vaccine.

Why should you use PYRAMID?

Cattle producer James Tanner shares a little about his operation and why Pyramid® 5 is a good fit for helping to protect calves.

Product Description

The PYRAMID family of modified live virus vaccines are single-dose products providing broad coverage of bovine viral diarrhea virus (BVDV) Types 1 and 2, infectious bovine rhinotracheitis (IBR), parainfluenza-3 (PI3) and bovine respiratory syncytial virus (BRSV), with options for various combinations dependent upon product. PYRAMID delivers enhanced efficacy with the help of the MetaStim® adjuvant system, enhancing the animal’s response to the vaccine for greater protection.

  • Provides broad coverage against BVDV Types 1 and 2, IBR, BRSV and PI3 
  • Available in a variety of different combinations, including 5-way lepto or Lepto pomona-hardjo 
  • Single dose protection
  • Meets BQA guidelines for both dosage level and administration route

The Pyramid® Family:

  • PYRAMID 10

(Learn more about combos)

  • PYRAMID 3 + Presponse® SQ
  • PYRAMID 4 + Presponse® SQ
  • PYRAMID 5 + Presponse® SQ

Features and Benefits

  • The PYRAMID family of vaccines provides broad coverage for BVDV Types 1 and 2, IBR, BRSV and PI3 with only a single dose.  They contain the MetaStim® adjuvant system to maximize the animal’s response for greater protection.
  • PYRAMID vaccines are available in varying product combinations, including convenient combinations with 5-way lepto or Lepto pomona-hardjo protection.
  • Most products in the PYRAMID family contain both BVDV Type 1 (Singer) and 2 (5912), which are specifically selected for broad BVDV coverage. 
  • PYRAMID’s whole herd claim allows producers the flexibility to vaccinate pregnant cows, or calves nursing pregnant cows, if the cows were vacinated pre-breeding with PYRAMID 3, PYRAMID 5, or PYRAMID 10 product.

Dosage Information

  • 2 mL administered subcutaneously
  • Annual revaccination required
  • See individual product labels for complete dosage information

Safety Information

  • A small percentage of animals may show transient mild injection site swelling.
  • Do not vaccinate within 21 days before slaughter.
  • Burn container and all unused contents.
  • In case of anaphylactoid reaction, administer epinephrine.
  • Store in the dark at 35 - 45°F (2 - 7°C). Avoid freezing.
  • See individual product labels for details regarding use in pregnant cows or calves nursing pregnant cows.

Product Resources

Contact Information

  • Boehringer Ingelheim Vetmedica, Inc.

    Cattle Division

    3239 Satellite Blvd NW,
    Duluth, GA 64506

    • Phone 866-638-2226
    • Fax 816-326-9167
    • e-mail