Live Therapeutics

Throughout a bird’s life, challenges occur that can disrupt the normal function in the intestinal tract. These challenges can include protozoal, bacterial, viral infections, and environmental stresses that can damage the delicate cells that line the intestines—disrupting the normal balance of flora that aid in digestion, processing of nutrients, and immune responses.

The intestinal tract of the bird is a complex system designed to take nutrients in the form of poultry feed and efficiently convert it to growth. The poultry industry is based on this simple concept of feed conversion—how efficiently broilers accomplish this task of reaching their growth potential. With the current shift in production strategies toward using little to no antibiotics, alternative products to replace antibiotics that promote a healthy intestinal balance are needed. A wide variety of these products are found on the market including various prebiotics, yeast extracts, phytochemicals, or essential acids. 

Probiotics in feed have been around for many years within the poultry industry, to support feed conversion and improve weight gain. A different type of probiotic has been developed which increases the average daily weight gain, improves food conversion ratio, and improves food safety from bacterial pathogens.1 These factors have a positive impact on the poultry industry while providing safe and healthy poultry for human consumption by reducing the pathogen load of Salmonella.

Complementing our leading poultry vaccines, Live Therapeutics includes probiotics to help you raise a healthy and cost-effective flock.

Live Therapeutics2

Live Therapeutics (also known as Live Bio Therapeutics) are:

  • Biological products that contain live organisms such as bacteria,
  • AND are products which produce beneficial results for your flock,
  • AND are not a vaccine.

Probiotics and Live Therapeutics

A successful probiotic must have characteristics such as resistance to the acidic environment of the stomach and the bile salts of the small intestine and also the capacity to adhere to and colonize the intestine.3

Boehringer Ingelheim Solutions**

In the U.S., Boehringer Ingelheim is already one of the industry leaders in poultry vaccination. With our research and development initiatives, we anticipate sharing this expertise with wider markets as the poultry industry evolves. Due to the decreased usage of antibiotics, producers are looking for alternatives that will allow them to produce meat with the lowest cost and highest quality. The well-being and overall health of the animal is an important factor for the producer and their customers. Boehringer Ingelheim’s legacy in biologics guides our focus on developing alternative solutions to the traditional pharmaceutical approaches. Currently, our Live Therapeutics line of products* includes the following brands:

To learn more about our Live Therapeutics or vaccines, talk to your Boehringer Ingelheim representative!


*Boehringer Ingelheim produces and markets several vaccines against poultry enteric diseases. However, be aware that NOT all aspects of the diseases mentioned on this page are addressed by a vaccine. Always consult the product label for exact vaccine indications.

**Many of Boehringer Ingelheim’s avian vaccines are only marketed and available in certain countries, sometimes under different trade names. Speak to your Boehringer Ingelheim representative or contact us to find out what’s available in your region.

References:

  1. Food and Agriculture Organization of the United Nations. Probiotics in Animal Nutrition, Production, Impact and Regulation. 2016. Rome. Page 15-31.
  2. Early Clinical Trials with Live Biotherapeutic Products: Chemistry, Manufacturing, and Control Information https://www.fda.gov/files/vaccines,%20blood%20&%20biologics/published/Early-Clinical-Trials-With-Live-Biotherapeutic-Products--Chemistry--Manufacturing--and-Control-Information--Guidance-for-Industry.pdf
  3. FAO/WHO, 2002; Mishra et all. 2005.
  4. Borda-Molina Daniel; Seifert Jana; Camarinha-Silva Amélia. Current Perspectives of the Chicken Gastrointestinal Tract and Its Microbiome, Institute of Animal Science. 2018. University of Hohnenheim, Stuttgart, Germany.
  5. Kers, Jannigje G.;1,2* Velkers Francisca C.;¹ Fischer Egil A. J.; Hermes Gerben D. A.² ; Stegeman J. A.;1 Hauke Smidt2. Host and Environmental Factors Affecting the Intestinal Microbiota in Chickens.1 2018. Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands;² Laboratory of Microbiology, Wageningen University & Research, Wageningen, Netherlands.
  6. Stanley, Dragana; Huges Robert J.; Moore Robert J. Microbiota of the chicken gastrointestinal tract: influence on health, productivity and disease. 2014.

 

FloraMax® is a registered trademark of Novozymes A/S.
FloraMax®-PW is manufactured by Novozymes Biologicals Inc. and distributed by Boehringer Ingelheim Animal Health USA Inc.
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