The ultimate in customization for control of three respiratory diseases in swine: PCV2, M. hyo and PRRS

3FLEX® is the only single-dose, three-way vaccine licensed by the USDA for use in swine to control PCV2, M. hyo and Porcine Reproductive & Respiratory Syndrome (PRRS). As part of the FLEX Family™ of swine vaccines, 3FLEX® provides you the additional ability to customize a disease control program where all three diseases are present.

Ingelvac 3FLEX® Vaccine Overview

  • Customized control of three swine diseases
    3FLEX® is the only USDA-approved combination vaccine for protection against PCV2, M. hyo and PRRS in a single injection.
  • Fewer injections
    3FLEX® is easy to mix and is administered in a single 2 mL injection to pigs 3 weeks of age or older, reducing labor and stress of injecting pigs multiple times.
  • Research proven effective
    Extensive research studies show lack of interference between antigens and a high level of immunization and product efficacy against three diseases.
  • FLEX Family™ product with ImpranFLEX®
    3FLEX® is part of the FLEX Family™ of vaccines from BIVI and contains the unique ImpranFLEX® aqueous-based polymer adjuvant for strong immune response and low risk of adverse reactions.

For most swine producers, a single 2 mL dose of 3FLEX® replaces multiple injections of monovalent vaccines; saving time, labor and the hassles and stress of handling pigs multiple times. More importantly, extensive research studies show that 3FLEX® consistently provides effective protection against clinical disease associated with PCV2, M. hyo and PRRS.

In addition, there is no interference between the individual antigens when administered to pigs as a single injection. This means 3FLEX® effectively immunizes pigs against all three diseases and there is low risk of adverse reactions.

No difference in serological PRRS response in 3 week old pigs vaccinated with either 3FLEX® or FLEXcombo® concurrently administered with Ingelvac PRRS® MLV Fangman T. et al. 2011. Leman P262.

3FLEX® Mixing Guide

Directions and dosage: Shake each bottle of liquid product before use. Insert a vented transfer spike into Ingelvac MycoFLEX®2 headspace bottle. Invert the Ingelvac CircoFLEX® 1 bottle over the Ingelvac MycoFLEX® 2. Transfer the full contents of the vaccine into the Ingelvac MycoFLEX® 2 bottle via the transfer spike and gently shake. Remove the Ingelvac CircoFLEX® 1 bottle and slowly insert the transfer spike into the Ingvelvac PRRS® MLV 3 vaccine bottle, releasing the vacuum. Transfer a portion of the mixed vaccine from the Ingelvac MycoFLEX® 2 bottle into the Ingelvac PRRS® MLV 3 bottle. The amount transferred needs to be enough to rehydrate the Ingelvac PRRS® MLV 3 product. Flip the Ingelvac PRRS® MLV 3 and Ingelvac MycoFLEX®2 bottles - still attached by transfer spike - to transfer rehydrated product back into the Ingelvac MycoFLEX® 2 bottle. Shake well and use immediately. Rehydrate only with the accompanying vaccines, do not mix other materials. Dosage: Using aseptic technique, inject a single 2 mL dose of vaccine intramuscularly. View printable PDF. 

Learn about other FLEX Family™ products

Contact Information

  • Boehringer Ingelheim Vetmedica, Inc.

    Swine Division

    3902 Gene Field Road
    St. Joseph, Missouri 64506

    • Phone 866-638-2226
    • Fax 816-676-4754
    • e-mail