The first FLEX Family™ vaccine for PCV2 protection in a single injection

Ingelvac CircoFLEX® was the first in the FLEX Family of swine vaccines and one of the most revolutionary PCV2 vaccines on the market. As a result, it has built a reputation for providing safe, effective control of porcine circovirus associated disease (PCVAD) in pigs three weeks of age or older from a single dose.

Ingelvac CircoFLEX® Vaccine Overview

  • Timing of vaccination
    Single-dose, 1 mL vaccine approved for pigs 3 weeks of age or older.
  • Long duration of immunity
    Ingelvac CircoFLEX® provides at least 4 months of immunity, long enough to last through the critical grow-finish stage.
  • Rapid onset of immunity
    Unlike two-dose products, it provides effective immune response within 2 weeks after single dose vaccination.
  • Excellent safety profile
    Because it contains both PCA™ and ImpranFLEX®, Ingelvac CircoFLEX® provides a strong immune response with low risk of injection site or other adverse reactions in pigs.
  • PQA Plus® and labor-saving benefits
    Single-dose administration reduces pig handling and stress by reducing labor and number of injections.

PCA™ and ImpranFLEX®

Unlike all other PCV2 vaccines on the market, Ingelvac CircoFLEX® contains the unique combination of Purified Circovirus Antigen (PCA™) and ImpranFLEX®. PCA™ is the Ingelvac CircoFLEX® antigen where extraneous baculovirus from the virus-like particle (VLP) is removed, resulting in a highly refined vaccine.

ImpranFLEX® is a proprietary water-based polymer adjuvant found in all FLEX Family™ vaccines. These two innovative vaccine technologies work together to generate a strong immune response and low risk of adverse reactions in vaccinated pigs.


Effectively Diagnosing PCVAD

The American Association of Swine Veterinarians has adopted the following criteria for confirming a diagnosis of PCVAD:

  • Clinical signs

    Progressive weight loss, Porcine Dermatitis Nephropathy Syndrome (PDNS), pneumonia, diarrhea, and/or reproductive disease.

  • Increased mortality rates

    Doubling of historical death loss due to acute disease infection.

  • Histologic lesions

    Lymphoid depletion with or without granulomatous inflammation.

  • Diagnostic results

    PCV2 detection in lesions via PCV2 immunohistochemistry (IHC) when associated with characteristic lung lesions or in fetal myocarditis lesions in reproductive PCVAD.


a Waddell.2012.IPVS.p935
b Sponheim.2012.Leman.p210
c Johnson.2013.AASV.p435-436

Learn about other FLEX Family™ products

Contact Information

  • Boehringer Ingelheim Vetmedica, Inc.

    Swine Division

    3902 Gene Field Road
    St. Joseph, Missouri 64506

    • Phone 866-638-2226
    • Fax 816-676-4754
    • e-mail